PLEASE WAIT, LOADING

Iron replacement therapy in patients with heart failure

Iron replacement therapy in patients with heart failure

iron-supplements_fe.webp

Iron replacement therapy in patients with heart failure.

Most patients with heart failure and anemia demonstrate iron deficiency, which is often accompanied by anemia. Iron deficiency is generally defined as having a serum ferritin level <100 µg/L or, provided that ferritin level was >300 µg/L, a transferrin saturation (TSAT) <20%.

The IRONMAN randomized trial showed that, overall, for patients with heart failure who fulfilled the above definition of iron deficiency, IV iron increased hemoglobin levels, improved quality of life, and reduced the rates of hospitalization for heart failure but did not improve walking distance or reduce mortality.

According to a recent publication, the clinical response appears even greater in certain individuals with anemia with TSAT < 20% and ferritin > 100 µg/L.

This might identify a specific group of heart failure patients, who may obtain a significant benefit from intravenous iron.

Reference:
European Heart Journal
Intravenous iron for heart failure, iron deficiency definitions, and clinical response: the IRONMAN trial
Eur Heart J 2024 Mar 06

Dr Yiannis Panayiotides


Dr_Yiannis_panagiotides_logo

Είναι αδύνατο να ξέρει την ιατρική, αυτός που δεν ξέρει ακριβώς τι είναι ο άνθρωπος. ΙΠΠΟΚΡΑΤΗΣ




Dr_Yiannis_panagiotides_logo

It is impossible for one to know medicine if he doesn’t know what a human being is. HIPPOCRATES






Copyright by Dr Yiannis Panayiotides 2018. All rights reserved.



Copyright by Dr Yiannis Panayiotides 2018. All rights reserved.